The Broken Stocks list · updated 2026-05-14
2,524 U.S. stocks down 20% or more from a 52-week high.
Falling knives, broken trends, and Watch-tier early declines. Filter by tier, sector, or ticker. Tiering is computed daily from decline depth, time-frame continuity, and decline sigma.
| Tier | Ticker | Company | Decline | Sigma | TFC | Price | Trigger |
|---|---|---|---|---|---|---|---|
| Red List |  OPRX |
OptimizeRx Corporation · Healthcare | -76.7% | 6.3σ | 2/5 | $5.18 | decline depth |
| Red List |  DOCS |
Doximity, Inc. · Healthcare | -76.5% | 5.9σ | 3/5 | $18.01 | decline depth |
| Red List |  UPB |
Upstream Bio, Inc. · Healthcare | -73.9% | 6.7σ | 4/5 | $8.79 | decline depth |
| Red List |  INSP |
Inspire Medical Systems, Inc. · Healthcare | -73.5% | 6.8σ | 5/5 | $42.66 | decline depth |
| Red List |  PHR |
Phreesia, Inc. · Healthcare | -73.2% | 4.6σ | 4/5 | $8.77 | decline depth |
| Red List Recovering |  MLTX |
MoonLake Immunotherapeutics · Healthcare | -70.7% | 4.2σ | 1/5 | $18.39 | decline depth |
| Red List |  WVE |
Wave Life Sciences Ltd. · Healthcare | -68.2% | 3.5σ | 3/5 | $6.90 | decline depth |
| Red List |  QDEL |
QuidelOrtho Corporation · Healthcare | -68.0% | 3.7σ | 3/5 | $11.39 | decline depth |
| Red List |  ARCT |
Arcturus Therapeutics Holdings · Healthcare | -67.6% | 4.8σ | 2/5 | $7.83 | decline depth |
| Red List |  ATEC |
Alphatec Holdings, Inc. · Healthcare | -67.5% | 3.8σ | 4/5 | $7.57 | decline depth |
| Red List |  RXST |
RxSight, Inc. · Healthcare | -66.4% | 6.7σ | 5/5 | $5.63 | decline depth |
| Red List |  HIMS |
Hims & Hers Health, Inc. · Healthcare | -65.6% | 4.5σ | 4/5 | $24.24 | decline depth |
| Red List |  ADMA |
ADMA Biologics Inc · Healthcare | -62.0% | 6.0σ | 5/5 | $8.50 | decline depth |
| Red List |  RGNX |
REGENXBIO Inc. · Healthcare | -61.4% | 5.0σ | 3/5 | $6.25 | decline depth |
| Red List Recovering |  QURE |
uniQure N.V. · Healthcare | -61.2% | 1.6σ | 2/5 | $27.75 | decline depth |
| Red List |  SLP |
Simulations Plus, Inc. · Healthcare | -60.7% | 5.5σ | 4/5 | $13.38 | decline depth |
| Red List |  PRGO |
Perrigo Company plc · Healthcare | -60.5% | 4.7σ | 3/5 | $10.84 | decline depth |
| Red List Recovering |  PRCT |
PROCEPT BioRobotics Corporation · Healthcare | -60.5% | 2.7σ | 3/5 | $26.38 | decline depth |
| Red List |  AZTA |
Azenta, Inc. · Healthcare | -59.7% | 6.0σ | 4/5 | $16.80 | decline depth |
| Red List Recovering |  JANX |
Janux Therapeutics, Inc. · Healthcare | -59.3% | 7.1σ | 4/5 | $14.39 | decline depth |
| Red List |  PODD |
Insulet Corporation · Healthcare | -58.1% | 6.2σ | 4/5 | $148.68 | decline depth |
| Red List |  SPRY |
ARS Pharmaceuticals, Inc. · Healthcare | -58.0% | 5.4σ | 3/5 | $7.94 | decline depth |
| Red List |  SRPT |
Sarepta Therapeutics, Inc. · Healthcare | -57.7% | 6.4σ | 1/5 | $18.68 | decline depth |
| Red List |  ZBIO |
Zenas BioPharma, Inc. · Healthcare | -57.6% | 2.9σ | 2/5 | $18.90 | decline depth |
| Red List Recovering |  CLPT |
ClearPoint Neuro Inc. · Healthcare | -57.6% | 3.0σ | 3/5 | $12.77 | decline depth |
| Red List |  CSTL |
Castle Biosciences, Inc. · Healthcare | -57.4% | 5.5σ | 2/5 | $18.88 | decline depth |
| Red List |  TEM |
Tempus AI, Inc. · Healthcare | -56.4% | 5.7σ | 2/5 | $45.48 | decline depth |
| Red List |  NERV |
Minerva Neurosciences, Inc · Healthcare | -55.9% | 8.2σ | 2/5 | $5.50 | decline depth |
| Red List |  ZTS |
Zoetis Inc. · Healthcare | -55.5% | 7.8σ | 5/5 | $75.48 | decline depth |
| Red List |  DNA |
Ginkgo Bioworks Holdings, Inc. · Healthcare | -55.4% | 4.1σ | 2/5 | $7.85 | decline depth |
| Red List |  BHVN |
Biohaven Ltd. · Healthcare | -55.1% | 4.8σ | 3/5 | $9.02 | decline depth |
| Red List |  FULC |
Fulcrum Therapeutics, Inc. · Healthcare | -54.8% | 5.5σ | 4/5 | $7.11 | decline depth |
| Red List |  WAY |
Waystar Holding Corp. · Healthcare | -54.6% | 7.6σ | 4/5 | $18.83 | decline depth |
| Red List |  WEAV |
Weave Communications, Inc. · Healthcare | -54.5% | 3.5σ | 5/5 | $5.15 | decline depth |
| Red List Recovering |  CRMD |
CorMedix Inc. · Healthcare | -54.5% | 4.3σ | 2/5 | $7.93 | decline depth |
| Red List |  SDGR |
Schrodinger, Inc. · Healthcare | -54.3% | 2.6σ | 4/5 | $12.62 | decline depth |
| Red List |  NTLA |
Intellia Therapeutics, Inc. · Healthcare | -53.7% | 4.3σ | 2/5 | $13.09 | decline depth |
| Red List |  TNDM |
Tandem Diabetes Care, Inc. · Healthcare | -52.3% | 7.1σ | 1/5 | $14.15 | decline depth |
| Red List |  KROS |
Keros Therapeutics, Inc. · Healthcare | -51.3% | 5.3σ | 2/5 | $10.99 | decline depth |
| Red List Recovering |  ALGS |
Aligos Therapeutics, Inc. · Healthcare | -51.1% | 3.1σ | 2/5 | $6.69 | decline depth |
| Red List |  BSX |
Boston Scientific Corporation · Healthcare | -51.1% | 6.6σ | 5/5 | $53.55 | decline depth |
| Red List |  AVTR |
Avantor, Inc. · Healthcare | -50.2% | 4.8σ | 4/5 | $7.94 | decline depth |
| Red List |  ATRA |
Atara Biotherapeutics, Inc. · Healthcare | -49.9% | 1.1σ | 3/5 | $9.59 | decline depth |
| Red List |  VEEV |
Veeva Systems Inc. · Healthcare | -49.7% | 4.2σ | 4/5 | $156.25 | decline depth |
| Red List |  CRVS |
Corvus Pharmaceuticals, Inc. · Healthcare | -49.3% | 5.1σ | 2/5 | $13.65 | decline depth |
| Red List |  CVRX |
CVRx, Inc. · Healthcare | -49.2% | 4.9σ | 2/5 | $5.74 | decline depth |
| Red List Recovering |  VRDN |
Viridian Therapeutics, Inc. · Healthcare | -49.2% | 1.8σ | 3/5 | $17.43 | decline depth |
| Red List |  PBH |
Prestige Consumer Healthcare In · Healthcare | -48.6% | 9.2σ | 2/5 | $45.93 | decline depth |
| Red List Recovering |  GRAL |
GRAIL, Inc. · Healthcare | -48.0% | 1.4σ | 2/5 | $61.80 | decline depth |
| Red List Recovering |  FLGT |
Fulgent Genetics, Inc. · Healthcare | -47.8% | 1.5σ | 3/5 | $16.19 | decline depth |
| Red List |  RNAC |
Cartesian Therapeutics, Inc. · Healthcare | -46.9% | 2.4σ | 3/5 | $8.27 | decline depth |
| Red List |  IRTC |
iRhythm Holdings, Inc. · Healthcare | -46.1% | 4.0σ | 3/5 | $114.16 | decline depth |
| Red List |  INSM |
Insmed Incorporated · Healthcare | -45.6% | 3.3σ | 3/5 | $115.62 | decline depth |
| Red List |  AMPH |
Amphastar Pharmaceuticals, Inc. · Healthcare | -44.7% | 5.1σ | 4/5 | $17.30 | decline depth |
| Red List |  ICLR |
ICON plc · Healthcare | -44.5% | 2.2σ | 2/5 | $117.09 | decline depth |
| Red List |  ORIC |
Oric Pharmaceuticals, Inc. · Healthcare | -44.1% | 9.5σ | 2/5 | $8.34 | decline depth |
| Red List |  BAX |
Baxter International Inc. · Healthcare | -44.1% | 3.4σ | 4/5 | $17.78 | decline depth |
| Red List Recovering |  VTYX |
Ventyx Biosciences, Inc. · Healthcare | -44.0% | — | 0/5 | $14.00 | decline depth |
| Red List |  MOH |
Molina Healthcare Inc · Healthcare | -43.0% | 2.0σ | 3/5 | $186.80 | decline depth |
| Red List |  MLYS |
Mineralys Therapeutics, Inc. · Healthcare | -42.8% | 4.6σ | 4/5 | $27.27 | decline depth |
| Red List |  QGEN |
Qiagen N.V. · Healthcare | -42.4% | 7.0σ | 4/5 | $33.29 | decline depth |
| Red List Recovering |  OCUL |
Ocular Therapeutix, Inc. · Healthcare | -42.2% | 2.9σ | 3/5 | $9.50 | decline depth |
| Red List Recovering |  CRBP |
Corbus Pharmaceuticals Holdings · Healthcare | -41.7% | 2.4σ | 2/5 | $11.98 | decline depth |
| Red List |  PSNL |
Personalis, Inc. · Healthcare | -41.6% | 2.8σ | 1/5 | $6.71 | decline depth |
| Red List |  EBS |
Emergent BioSolutions Inc. · Healthcare | -41.6% | 4.6σ | 3/5 | $8.21 | decline depth |
| Red List |  SMMT |
Summit Therapeutics Inc. · Healthcare | -41.5% | 5.7σ | 3/5 | $18.14 | decline depth |
| Red List Recovering |  SLNO |
Soleno Therapeutics, Inc. · Healthcare | -41.3% | 0.5σ | 5/5 | $52.99 | decline depth |
| Red List |  RGEN |
Repligen Corporation · Healthcare | -41.2% | 7.5σ | 3/5 | $103.38 | decline depth |
| Red List |  NVO |
Novo Nordisk A/S · Healthcare | -41.0% | 2.0σ | 3/5 | $45.80 | decline depth |
| Red List |  ALNY |
Alnylam Pharmaceuticals, Inc. · Healthcare | -40.8% | 6.0σ | 3/5 | $293.45 | decline depth |
| Red List Recovering |  SGRY |
Surgery Partners, Inc. · Healthcare | -40.1% | 3.5σ | 3/5 | $14.48 | decline depth |
| Red List |  CNMD |
CONMED Corporation · Healthcare | -39.8% | 5.2σ | 5/5 | $36.34 | time-frame continuity |
| Red List |  RARE |
Ultragenyx Pharmaceutical Inc. · Healthcare | -39.1% | 3.3σ | 5/5 | $25.80 | time-frame continuity |
| Red List |  TCMD |
Tactile Systems Technology, Inc · Healthcare | -39.0% | 5.0σ | 1/5 | $23.04 | decline depth |
| Red List |  TECH |
Bio-Techne Corp · Healthcare | -37.9% | 5.2σ | 3/5 | $44.74 | decline depth |
| Red List Recovering |  ABT |
Abbott Laboratories · Healthcare | -37.7% | 8.1σ | 5/5 | $84.90 | time-frame continuity |
| Red List |  MMSI |
Merit Medical Systems, Inc. · Healthcare | -37.5% | 4.9σ | 5/5 | $62.56 | time-frame continuity |
| Red List |  XRAY |
DENTSPLY SIRONA Inc. · Healthcare | -37.4% | 8.6σ | 1/5 | $10.41 | decline sigma |
| Red List |  VNDA |
Vanda Pharmaceuticals Inc. · Healthcare | -35.7% | 4.3σ | 2/5 | $6.39 | decline depth |
| Red List |  TENX |
Tenax Therapeutics, Inc. · Healthcare | -35.3% | 5.9σ | 2/5 | $11.90 | decline depth |
| Red List |  ARVN |
Arvinas, Inc. · Healthcare | -35.1% | 6.9σ | 3/5 | $9.42 | decline depth |
| Red List |  IBRX |
ImmunityBio, Inc. · Healthcare | -34.4% | 1.7σ | 2/5 | $8.15 | decline depth |
| Red List |  MEDP |
Medpace Holdings, Inc. · Healthcare | -33.4% | 3.9σ | 1/5 | $419.17 | decline depth |
| Red List |  COO |
The Cooper Companies, Inc. · Healthcare | -32.8% | 10.7σ | 3/5 | $60.38 | decline sigma |
| Red List |  VREX |
Varex Imaging Corporation · Healthcare | -31.2% | 4.7σ | 3/5 | $10.02 | decline depth |
| Red List |  ALHC |
Alignment Healthcare, Inc. · Healthcare | -30.6% | 6.4σ | 3/5 | $16.56 | decline depth |
| Red List Recovering |  INNV |
InnovAge Holding Corp. · Healthcare | -30.5% | 5.9σ | 1/5 | $7.43 | decline depth |
| Red List |  TMO |
Thermo Fisher Scientific Inc · Healthcare | -30.3% | 6.7σ | 2/5 | $448.21 | decline depth |
| Red List Recovering |  CHE |
Chemed Corp · Healthcare | -26.7% | 2.9σ | 5/5 | $426.21 | time-frame continuity |
| Red List |  ANNX |
Annexon, Inc. · Healthcare | -25.2% | 8.5σ | 2/5 | $5.37 | decline sigma |
| Red List Recovering |  SYK |
Stryker Corporation · Healthcare | -24.0% | 6.1σ | 5/5 | $305.51 | time-frame continuity |
| Red List |  ALGN |
Align Technology, Inc. · Healthcare | -22.9% | 9.3σ | 1/5 | $160.53 | decline sigma |
| Red List |  STOK |
Stoke Therapeutics, Inc. · Healthcare | -22.0% | 8.7σ | 1/5 | $31.36 | decline sigma |